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Aygestin 5 mg

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General information about Aygestin.

Aygestin is a synthesized female hormone progesterone.

In women with a normal menstrual cycle, progesterone is synthesized by the corpus luteum of the ovary. In small quantities, it is formed in men and women in the adrenal cortex during the exchange of steroids.

During the maturation of the follicle (follicular phase of the menstrual cycle), the level of progesterone in the blood remains low. With ovulation, which ends with the rupture of the follicle and the formation of the corpus luteum, the synthesis of progesterone increases significantly, its level reaches a maximum about 7 days before the onset of menstruation.

If the fertilization of the egg does not occur, in the last 4 days of the cycle, the level of progesterone decreases due to regression of the corpus luteum. If fertilization has occurred, the corpus luteum maintains progesterone synthesis at a level close to the middle of the luteal phase until about 6 weeks of gestation. By this time, the placenta becomes the main source of progesterone, and the level of this hormone rises.

The biological role of progesterone is to prepare the endometrium for implantation of a fertilized egg, and after implantation, it contributes to the preservation of pregnancy.

Hormone therapy with Progesterone: what is it and who needs it?

Progesterone (Aygestin 5 mg) is a sex hormone produced by the ovaries after ovulation, the placenta and the adrenal glands. It is found not only in the female, but also in the male body. Its role for a woman of any age, and especially during pregnancy, is difficult to overestimate. Aygestin can both help to get pregnant and, on the contrary, prevent conception. Therefore, every woman should know the knowledge of its properties and capabilities.

What is the role of progesterone in the female body?

In women, this hormone is involved in the regulation of menstruation and fertility. It is secreted during the second half of the menstrual cycle, thickening the wall of the uterus and preparing it for a fertilized egg. If conception does not occur, then the level of progesterone falls, the endometrium collapses and menstrual bleeding appears. But if a woman becomes pregnant, the placenta will continue to produce enough progesterone and estrogen to stop ovulation. Aygestin 5 mg is critical for creating favorable conditions for conception and maintaining a healthy pregnancy (increased arterial blood supply to the fetus, glycogen production, protection from bacteria penetration into the uterus due to the thickening of the cervix), preventing premature birth.

Progesterone affects all stages of pregnancy, from the stage of ovulation and fertilization to lactation before childbirth.

Even during periods when a woman is not pregnant or ovulating, progesterone performs many different processes in her body that affect her health every day:

1. Aygestin 5 mg helps maintain optimal levels of zinc and copper, promoting good blood clotting;

2. The drug helps the body to properly use the reserves of fat in the body and generate energy from them;

3. The hormone reduces inflammation in the body and strengthens the immune system;

4. Aygestin is essential for the process of insulin secretion from the pancreas;

5. It plays an important role in the production of collagen protein, providing elasticity to the skin, strengthening bones and protecting the nervous system.

With age, the level of sex hormones begins to decline and gradually leads to menopause. Together with this, the menstrual cycle disappears, the aging process is activated due to a decrease in collagen production, wrinkles appear and bones weaken.

Who needs progesterone hormone therapy?

Progesterone hormone therapy is prescribed for women who have low levels of the hormone in their blood, causing the following problems:

1. Difficulties with conception;

2. Endometriosis;

3. Depletion of bone tissue (osteoporosis);

4. Irregular menstrual cycle;

5. Autoimmune diseases;

6. Fibrocystic breast disease;

7. Ovarian cysts;

8. Myalgia;

9. Premenstrual syndrome;

10. Menopause.

Infertility treatment.

Aygestin 5 mg is used to increase the likelihood of embryo establishment. It promotes the thickening of the lining of the uterus after ovulation and increases the likelihood of fetal survival. In many cases, infertility treatment, as well as in vitro fertilization, is accompanied by ovarian hyperstimulation, which disrupts the natural production of this hormone.

Aygestin 5 mg is necessary not only at the beginning of pregnancy, but also during the first trimester of pregnancy to ensure the correct development of the fetus. Women who become pregnant as a result of fertility treatment or who had an abortion in the early stages of pregnancy will be prescribed progesterone for several weeks until the placenta itself begins to produce the hormone instead of the ovaries.

Early exposure of the fetus to progesterone during fertility treatment increases the risk of having a child with autism by 1.5 times.

Preventing pregnancy.

As strange as it may sound, Aygestin 5 mg is used not only to treat infertility, but also to prevent pregnancy. It turns out that a large amount of this hormone inhibits ovulation. In addition, if ovulation occurs but no subsequent fertilization occurs, the presence of the hormone in the body stops the maturation of additional eggs and prevents further fertilization throughout the cycle.

Today it is common to use progestins, synthetic hormones that are used as a contraceptive as an emergency contraceptive or in the form of hormonal injections for long-term protection. However, estrogen-based female hormone preparations are considered to be more effective in this regard.

Prevention of oncology.

Aygestin 5 mg plays an important role in the prevention of endometrial cancer. The combination of sex hormones prevents estrogen from forming the endometrium, which can trigger the growth of cancer cells. Progesterone can be prescribed as a combined hormonal drug, as a local vaginal agent and as an intrauterine device.

Relief of menopause.

Aygestin 5 mg has also been found to help treat various symptoms of menopause. Taking hormonal pills helps to reduce the frequency and intensity of hot flashes, vaginal dryness, mood changes, prevents the development of uterine cancer cells, stops the process of bone wasting, prevents the development of osteoporosis, and slows down the natural aging process.

Prevention of premature birth.

Delivery earlier than 37 full weeks of pregnancy has been the most pressing problem in obstetrics for many years. About 60-80% of newborn deaths occur precisely due to premature birth. And progesterone was recognized as a hubbub, which has proven itself well in the prevention of this obstetric problem. Hormone therapy from weeks 16 to 34 has been proven to be effective against miscarriages and early labor. It prevents uterine contractions and prepares the breast for lactation.

Forms of hormonal progesterone preparations.

Progesterone drugs are available in various forms: vaginal gel, vaginal capsules, muscle injections, vaginal coils, capsules and oral tablets.

All progesterone preparations (Aygestin 5 mg) taken to support pregnancy are not recommended for oral administration due to the relatively poor absorption when taken this way. Most of them come in the form of vaginal capsules, where the absorption process is more successful.

Oral administration is indicated for the treatment of progesterone deficiency disorders in non-pregnant women, such as premenstrual syndrome, menstrual syndrome, uterine bleeding, and endometrial hyperplasia.

Hormone medications should only be taken under medical supervision.

Are there any side effects from Aygestin hormone?

Due to the use of various progesterone medications, there is a risk of blood clots, strokes, heart attacks, and even breast cancer. Its use is prohibited for women with circulatory problems, serious liver disease, breast or uterine cancer, unexplained vaginal bleeding. In addition, women experience weight gain and hair loss.

Injection hormone therapy often causes swelling and redness, accompanied by pain at the injection site. The use of vaginal forms of drugs can cause local discomfort and itching. Progesterone cream is generally safe to use. However, women with cancer problems should consult a doctor before using such a hormonal agent. Women taking birth control pills or synthetic progesterone should also avoid using topical products without consulting a gynecologist.

How to measure progesterone levels?

The amount of sex hormones is determined by analyzing venous blood in any diagnostic laboratory. Women are advised to undergo it on days 21-23 of the menstrual cycle. Before donating blood, the last meal should be no later than 2-3 hours. You can drink water. It is important to stop taking steroid and thyroid hormones at least two days before going to the laboratory. It is also recommended to avoid physical and emotional stress before the examination.